Longitudinal Depolarization Gradients Along the Somatodendritic Axis of CA1 Pyramidal Cells: A Novel Feature of Spreading Depression
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چکیده
منابع مشابه
Longitudinal depolarization gradients along the somatodendritic axis of CA1 pyramidal cells: a novel feature of spreading depression.
We studied the subcellular correlates of spreading depression (SD) in the CA1 rat hippocampus by combining intrasomatic and intradendritic recordings of pyramidal cells with extracellular DC and evoked field and unitary activity. The results demonstrate that during SD only specific parts of the dendritic membranes are deeply depolarized and electrically shunted. Somatic impalements yielded near...
متن کاملTRANSLATIONAL PHYSIOLOGY Longitudinal Depolarization Gradients Along the Somatodendritic Axis of CA1 Pyramidal Cells: A Novel Feature of Spreading Depression
Canals, S., I. Makarova, L. López-Aguado, C. Largo, J. M. Ibarz, and O. Herreras. Longitudinal depolarization gradients along the somatodendritic axis of CA1 pyramidal cells: a novel feature of spreading depression. J Neurophysiol 94: 943–951, 2005. First published March 30, 2005; doi:10.1152/jn.01145.2004. We studied the subcellular correlates of spreading depression (SD) in the CA1 rat hippoc...
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Evidence for different physiological properties along the hippocampal longitudinal axis is emerging. Here, we examined the electrophysiological features of neurons at different dorso-ventral sites of the mouse CA1 hippocampal region. Cell position was defined with respect to longitudinal coordinates of each slice. We measured variations in neuronal excitability, subthreshold membrane properties...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2005
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.01145.2004